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Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.

Jiao LuoQi XuBo JiangRenshuai ZhangXiaoling JiaXiangqian LiLijun WangChuanlong GuoNing WuDayong Shi
Published in: British journal of pharmacology (2017)
Our results indicate that HPN is a specific PTP1B inhibitor, with anti-diabetic properties and good cell permeability and oral availability.
Keyphrases
  • single cell
  • cell therapy
  • endothelial cells
  • type diabetes
  • stem cells
  • mesenchymal stem cells