[HLA genotypes associated with gastrointestinal symptoms in patients with spondyloarthritis without inflammatory bowel disease].
Maria Alejandra Meneses-ToroOmar Javier CalixtoViviana Parra-IzquierdoCristian Flórez-SarmientoJuliette de Ávila de-QuirogaAlejandro Ramos-CasallasLorena Chila-MorenoJuan Manuel Bello-GualteroWilson Bautista-MolanoConsuelo Romero-SanchezPublished in: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) (2024)
These findings indicate a potential genetic predisposition related to HLA genotypes that may increase the likelihood of food intolerance, gastrointestinal symptoms, and even visible and microscopic changes, specifically in the ileal tissue. The study highlights the presence of B*27 and other noteworthy HLA class I and class II genes (such as DRB1*14) in the diverse Colombian population.