DNA isolation from achieved formalin-fixed paraffin-embedded tissues in a series of 212 thyroid carcinoma cases: the influence of preanalytical factors on DNA quantity and purity.
Adela Nechifor-BoilăClaudia Violeta BănescuAncuta Elena ZahanValeriu MoldovanEmoke SzaszAngela BordaPublished in: Journal of investigative medicine : the official publication of the American Federation for Clinical Research (2019)
The maximal diameter of the tumor circled area, tumor volume and tumor fraction are important morphological factors that correlate with the DNA concentration and should be carefully assessed in routine practice prior to performing DNA isolation from FFPE tissues.