A new flavonoid derivative exerts antitumor effects against androgen-sensitive to cabazitaxel-resistant prostate cancer cells.

Renato NaitoHiroshi KanoTakashi ShimadaTomoyuki MakinoSuguru KadomotoHiroaki IwamotoHiroshi YaegashiKouji IzumiYoshifumi KadonoHiroki NakataYohei SaitoMasuo GotoKyoko Nakagawa-GotoAtsushi Mizokami

Published in: The Prostate (2021)

16MS7F1924 had sufficient antitumor activity against androgen-sensitive and cabazitaxel-resistant PCa cells and may be useful as a novel therapeutic agent overcoming hormone- and chemoresistant PCas.

Keyphrases

induced apoptosis
cell cycle arrest
mass spectrometry
multiple sclerosis
ms ms
signaling pathway
oxidative stress
pi k akt
water soluble