Tissue-Resident Memory CD8+ T Cells From Skin Differentiate Psoriatic Arthritis From Psoriasis.
Emmerik F A LeijtenTessa S van KempenMichel A Olde NordkampJuliette N PouwNienke J KleinrensinkNanette L VinckenJorre MertensDeepak M W BalakFleurieke H VerhagenSarita A HartgringErik LubbertsJanneke TekstraAridaman PanditTimothy R RadstakeMarianne BoesPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
Tissue-resident memory CD8+ T cells derived from the skin are enhanced in the circulation of patients with PsA compared to patients with psoriasis alone. This may indicate that aberrances in cutaneous tissue homeostasis contribute to arthritis development.