Telavancin pharmacokinetics in patients with chronic kidney disease receiving haemodialysis.
Katherine N GharibianSusan J LewisMichael HeungJonathan H SegalNoha N SalamaBruce A MuellerPublished in: The Journal of antimicrobial chemotherapy (2021)
Haemodialysis with high-permeability haemodialysers removes telavancin considerably (∼⅓ of body load). Telavancin 5 mg/kg every 48 h post-haemodialysis dosing is recommended, but dose adjustments may be warranted if haemodialysis starts within 3 h of telavancin administration.