Local recurrence after local excision of early rectal cancer: a meta-analysis of completion TME, adjuvant (chemo)radiation, or no additional treatment.
S E van OostendorpLisanne J H SmitsY VroomR DeteringM W HeymansL M G MoonsP J TanisE J R de GraafC CunninghamQuentin DenostM KustersJ B TuynmanPublished in: The British journal of surgery (2020)
There is a substantial risk of local recurrence in patients who receive no additional treatment after local excision, especially those with high-risk pT1 and pT2 rectal cancer. The lowest recurrence risk is provided by cTME; aCRT has outcomes comparable to those of cTME for high-risk pT1 tumours, but shows a higher risk for pT2 tumours.