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Systemic chemotherapy promotes HIF-1α-mediated glycolysis and IL-17F pathways in cutaneous T-cell lymphoma.

Bo WangKejia LiHonglin WangXiaoyan ShenJie Zheng
Published in: Experimental dermatology (2020)
CHOP chemotherapy promotes glycolysis and IL-17 pathways in a HIF-1α-dependent fashion. Furthermore, HIF-1α blockade is promising as an accompanying agent in systemic chemotherapy for patients with advanced CTCL.
Keyphrases
  • locally advanced
  • endothelial cells
  • diffuse large b cell lymphoma
  • squamous cell carcinoma
  • chemotherapy induced
  • radiation therapy