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Systemic chemotherapy promotes HIF-1α-mediated glycolysis and IL-17F pathways in cutaneous T-cell lymphoma.
Bo Wang
Kejia Li
Honglin Wang
Xiaoyan Shen
Jie Zheng
Published in:
Experimental dermatology (2020)
CHOP chemotherapy promotes glycolysis and IL-17 pathways in a HIF-1α-dependent fashion. Furthermore, HIF-1α blockade is promising as an accompanying agent in systemic chemotherapy for patients with advanced CTCL.
Keyphrases
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locally advanced
endothelial cells
diffuse large b cell lymphoma
squamous cell carcinoma
chemotherapy induced
radiation therapy