Brain morphometric features predict medication response in youth with bipolar disorder: a prospective randomized clinical trial.
Du LeiKun QinWenbin LiWalter H L PinayaMaxwell J TallmanL Rodrigo PatinoJeffrey R StrawnDavid FleckChristina C KleinSu LuiQiyong GongCaleb M AdlerAndrea MechelliJohn A SweeneyMelissa P DelBelloPublished in: Psychological medicine (2022)
These findings demonstrate that pre-treatment morphometric measures and acute brain morphometric changes can serve as medication response predictors in pediatric BD. Brain morphometric features may provide promising biomarkers for developing biologically-informed treatment outcome prediction and patient stratification tools for BD treatment development.
Keyphrases
- bipolar disorder
- clinical trial
- white matter
- resting state
- healthcare
- mental health
- emergency department
- functional connectivity
- liver failure
- major depressive disorder
- multiple sclerosis
- cerebral ischemia
- young adults
- combination therapy
- replacement therapy
- respiratory failure
- hepatitis b virus
- double blind
- extracorporeal membrane oxygenation
- aortic dissection