Cell-blocks are suitable material for programmed cell death ligand-1 immunohistochemistry: Comparison of cell-blocks and matched surgical resection specimens in lung cancer.

The results show that cytology CBs evaluated for PD-L1 IHC assay have high concordance with matched surgical resection specimens and can be used for assessing PD-L1 expression. Also, we propose that CBs are suitable materials for evaluating PD-L1 expression while simultaneously performing both diagnostic and molecular tests.