Influence of Sex on Outcomes After Thoracic Endovascular Repair for Type B Aortic Dissection.
Songyuan LuoYi ZhuEnmin XieHuanyu DingFan YangLyufan ChenJitao LiuYuan LiuLing XueRuixin FanJianFang LuoJiyan ChenPublished in: Angiology (2021)
We aimed to investigate whether sex differences influence the clinical outcomes of patients who undergo thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD). We retrospectively analyzed a prospectively maintained single-center cohort of patients with TBAD who underwent TEVAR between January 2010 and June 2017. We evaluated the in-hospital and long-term mortality and composite end point. Of the 913 patients, 793 (86.8%) were male and 120 (13.1%) were female. Compared to male patients, the female patients were older, more likely to have diabetes mellitus, but less likely to smoke or have hypertension. The proximal landing zone in 0 and 1 was higher in male patients (P = .023), who were more likely to require an aortic arch bypass. Endoleak, delirium, and ICU stay after stent-graft implantation were also more frequent in men. Sex factor was not associated with in-hospital or long-term mortality or the composite end point in the multivariable regression analyses and Cox regression model. The mean estimated survival time was similar between males and females (2462.9 ± 141.2 vs 2804.1 ± 117.4 days, P = .167) in the propensity score-matched cohort. Despite distinct characteristics between sex, there was no sex-related difference in long-term clinical outcomes after TEVAR for TBAD.
Keyphrases
- end stage renal disease
- aortic dissection
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- healthcare
- intensive care unit
- spinal cord
- emergency department
- metabolic syndrome
- spinal cord injury
- adipose tissue
- acute kidney injury
- cardiac surgery
- cardiovascular events
- adverse drug
- patient reported
- electronic health record