Association of prostate cancer polygenic risk score with number and laterality of tumor cores in active surveillance patients.

Jianfeng Xu William B IsaacsMufaddal MamawalaZhuqing ShiPatricia LandisJacqueline PetkewiczJun WeiChi-Hsiung WangW Kyle ResurreccionRong NaYasin BhanjiKristian NovakovicPatrick C WalshS Lilly ZhengBrian T HelfandChristian P Pavlovich

Published in: The Prostate (2021)

The associations of GRS with two measurements of PCa multifocality (core numbers and laterality) provide novel and consistent evidence for the link between inherited PCa risk and multifocal tumors.

Keyphrases

prostate cancer
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes