Apical left ventricular myocardial dysfunction is an early feature of cardiac involvement in myotonic dystrophy type 1.
Rodrigue GarciaQuentin LabarreBruno DegandPierre IngrandFrançois Le GalBenjamin BonnetAnne DelaubierClaire GuillouBarnabas GellenDamien CoisneClaire BouletiLuc ChristiaensPublished in: Echocardiography (Mount Kisco, N.Y.) (2017)
Despite preserved LVEF, DM1 patients exhibited significantly altered LV GLS, particularly at the apex, as compared with controls. The detection of impaired myocardial deformation at early stages of the disease might help to screen high-risk patients who need closer follow-up.
Keyphrases
- left ventricular
- end stage renal disease
- ejection fraction
- heart failure
- hypertrophic cardiomyopathy
- chronic kidney disease
- newly diagnosed
- acute myocardial infarction
- aortic stenosis
- cardiac resynchronization therapy
- prognostic factors
- left atrial
- oxidative stress
- early onset
- adipose tissue
- coronary artery disease
- metabolic syndrome
- patient reported outcomes
- aortic valve
- label free
- transcatheter aortic valve replacement
- patient reported
- neural network