Effects of Levistilide A on Hemorheology and Endothelial Cell Injury in Rats with Blood Stasis.

XiaoTong LiuMiJia ZhangYuJiao LiWenLu HeGuangHua LuQiong Wang QiaoZhi Wang

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

These findings demonstrated that LA has the ability to improve blood hypercoagulation and blood viscosity, and enhance the viability of cells. It is more likely that it exerts a protective effect on the endothelial cell through the PI3K-AKT-eNOs pathway. These results indicate LA will be a potential candidate to cure blood stasis with endothelial cell injury.

Keyphrases

endothelial cells
cell death
climate change
nitric oxide
cell cycle arrest
pi k akt
signaling pathway
vascular endothelial growth factor