DSC Brain Perfusion Using Advanced Deconvolution Models in the Diagnostic Work-up of Dementia and Mild Cognitive Impairment: A Semiquantitative Comparison with HMPAO-SPECT-Brain Perfusion.
Manuel Alexander SchmidtTobias EngelhornStefan LangHannes LueckingPhilip HoelterKilian FröhlichPhilipp RittJuan Manuel MalerTorsten KuwertJohannes KornhuberArnd DoerflerPublished in: Journal of clinical medicine (2020)
Advanced deconvolution DSC can reliably detect pathological perfusion alterations in FTD and MCI. Hence, this widely accessible technique has the potential to improve the diagnosis of dementia and MCI as part of an interdisciplinary multimodal imaging work-up. Advances in knowledge: Advanced DSC perfusion has a high potential in the work-up of suspected dementia and correlates with SPECT brain perfusion results in dementia and MCI.
Keyphrases
- mild cognitive impairment
- cognitive decline
- contrast enhanced
- resting state
- white matter
- healthcare
- functional connectivity
- magnetic resonance imaging
- high resolution
- cerebral ischemia
- risk assessment
- multiple sclerosis
- pet ct
- magnetic resonance
- human health
- pain management
- chronic pain
- climate change
- cognitive impairment