Ratios of specific IgG4 over IgE antibodies do not improve prediction of peanut allergy nor of its severity compared to specific IgE alone.
Mareen R DatemaEsben EllerAeilko H ZwindermanLars K PoulsenSerge A VersteegRonald van ReeCarsten Bindslev-JensenPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
IgE against Ara h 2 is the best biomarker for predicting peanut challenge outcomes including severity and IgG and IgG4 antibody ratios over IgE do not improve these outcomes.