Association between miRNAs in serum at 10-14 gestational weeks and spontaneous preterm delivery.

Tove WikströmSung Hye KimAnna-Lena LeverinUlla-Britt Wennerholm Bo Jacobson Lil ValentinPhillip R BennettVasso TerzidouHenrik Hagberg

Published in: Acta obstetricia et gynecologica Scandinavica (2024)

Our study shows that overexpression of miR-93-5p, miR-15b-5p, and miR-191-5p in serum at early gestation is associated with spontaneous PTD in a general population. Further research is needed to evaluate the potential of these miRNAs as future biomarkers for spontaneous PTD, as well as their pathophysiological role in spontaneous PTD.

Keyphrases

gestational age
pregnant women
weight gain
preterm infants
birth weight
transcription factor
weight loss