Neoadjuvant chemotherapy prior to radical hysterectomy in locally advanced cervical cancer: a systematic review and meta-analysis.
Chiara BorghiElena BiagioliJessica MauroAnna RobertoMartina BorgheseAlessandro BudaPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
The three-drug combination of cisplatin, paclitaxel, and ifosfamide or anthracyclines showed a higher rate of complete or optimal partial response, with the triple regimens having an advantage over the platinum-based schedules in terms of overall survival. Neoadjuvant chemotherapy followed by radical surgery should not be considered a standard of care in locally advanced cervical cancer.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- rectal cancer
- squamous cell carcinoma
- radiation therapy
- phase ii study
- sentinel lymph node
- minimally invasive
- healthcare
- coronary artery bypass
- quality improvement
- adverse drug
- drug induced
- percutaneous coronary intervention
- early stage
- clinical trial
- study protocol
- electronic health record