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Neoadjuvant chemotherapy prior to radical hysterectomy in locally advanced cervical cancer: a systematic review and meta-analysis.

Chiara BorghiElena BiagioliJessica MauroAnna RobertoMartina BorgheseAlessandro Buda
Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
The three-drug combination of cisplatin, paclitaxel, and ifosfamide or anthracyclines showed a higher rate of complete or optimal partial response, with the triple regimens having an advantage over the platinum-based schedules in terms of overall survival. Neoadjuvant chemotherapy followed by radical surgery should not be considered a standard of care in locally advanced cervical cancer.
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