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Defining and expanding the phenotype of QARS-associated developmental epileptic encephalopathy.

Katrine Marie JohannesenDiana MitterRobert JanowskiChristian RothJoseph ToulouseAnne-Lise PoulatDorothee M VilleNicolas ChatronEva H BrilstraKarin GeleijnsAlfred Peter BornScott McLeanKimberly NugentGareth S BaynamCathryn PoultonLauren DreyerDylan GrationSolveig SchulzAndrea DieckmannKatherine L HelbigAndreas MerkenschlagerRami Abou JamraAnja FinckElena GardellaHenrik HjalgrimGhayda M MirzaaFrancesco BrancatiTatjana BierhalsJonas DeneckeMaja HempelJohannes R LemkeGuido RubboliPetra MuschkeRenzo GuerriniAnnalisa VetroDierk NiessingGaëtan LescaRikke Steensjerre Moller
Published in: Neurology. Genetics (2019)
These data revealed first genotype-phenotype associations and may serve for improved interpretation of new QARS variants and well-founded genetic counseling.
Keyphrases
  • copy number
  • early onset
  • electronic health record
  • genome wide
  • single cell
  • big data
  • smoking cessation
  • gene expression
  • hiv testing
  • men who have sex with men
  • hiv infected
  • data analysis
  • antiretroviral therapy