Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study.
Helgi Freyr JónssonThor AspelundGudny EiriksdottirTamara B HarrisLenore J LaunerVilmundur G GudnasonPublished in: PloS one (2019)
Results from this population based study indicate that hyperuricemia in elderly females may be a rather frequent cause of intermittent hand joint pain, often in many joints. The most likely explanation relates to low-grade urate crystal induced inflammation. Our data do not allow for assessment of the severity of symptoms or whether they merit specific treatment, but intermittent hand joint pain was an independent predictor of worse general health. These findings may be an important contribution to the debate on whether hyperuricemia should be treated.
Keyphrases
- low grade
- chronic pain
- pain management
- neuropathic pain
- uric acid
- high intensity
- high grade
- healthcare
- oxidative stress
- public health
- middle aged
- physical activity
- metabolic syndrome
- mental health
- high glucose
- spinal cord
- spinal cord injury
- diabetic rats
- risk assessment
- machine learning
- risk factors
- big data
- sleep quality
- artificial intelligence