Impact of Insulin Sensitivity and β-Cell Function Over Time on Glycemic Outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): Differential Treatment Effects of Dual Therapy.
Kristina M UtzschneiderNaji YounesNicole M ButeraAshok BalasubramanyamRichard M BergenstalJoshua I BarzilayCyrus V DesouzaRalph A De FronzoTom ElasyJonathan KrakoffSteven E KahnNeda RasouliWilly M ValenciaWilliam I Sivitznull nullPublished in: Diabetes care (2024)
Insulin sensitivity and β-cell function affected treatment outcomes irrespective of drug assignment, with greater impact in the sitagliptin group on initial (short-term) HbA1c response in comparison with the glimepiride and liraglutide groups.