GATA4 Regulates Developing Endocardium Through Interaction With ETS1.
Pingzhu ZhouYan ZhangIsha SethiLincai YeMichael A TrembleyYangpo CaoBrynn N AkerbergFeng XiaoXiaoran ZhangKai LiBlake D JardinNeil MazumdarQing MaAibin HeBin ZhouWilliam T PuPublished in: Circulation research (2022)
Lineage selective non-pioneer TFs NKX2-5 and ETS1 guide the activity of pioneer TF GATA4 to bind and open chromatin and create active enhancers and mechanistically link ETS1 interaction to GATA4 regulation of endocardial development.