GATA4 Regulates Developing Endocardium Through Interaction With ETS1.

Pingzhu ZhouYan ZhangIsha SethiLincai YeMichael A TrembleyYangpo CaoBrynn N AkerbergFeng Xiao Xiaoran ZhangKai LiBlake D JardinNeil MazumdarQing Ma Aibin He Bin Zhou William T Pu

Published in: Circulation research (2022)

Lineage selective non-pioneer TFs NKX2-5 and ETS1 guide the activity of pioneer TF GATA4 to bind and open chromatin and create active enhancers and mechanistically link ETS1 interaction to GATA4 regulation of endocardial development.

Keyphrases

transcription factor
minimally invasive
gene expression
dna damage
dna methylation
genome wide
left ventricular