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A meissnerian neurofibroma: Case report of a rare neurofibroma variant.

Titilola SodeElaine KunzlerBianca UzomaMartha McColloughGregory A Hosler
Published in: Journal of cutaneous pathology (2020)
Structures resembling Meissner corpuscles have been described in various nerve sheath tumors, including schwannomas and neurofibromas. When present, they are focal or scattered, and rarely a prominent feature of the lesion. Here, we report a case of a 39-year-old female who presented with an isolated lesion on her abdomen. Histopathologically, the tumor was almost exclusively composed of Meissner corpuscle-like structures (pseudo-meissnerian bodies). At a small edge of the tumor, there were features of a classic neurofibroma, with a mixture of Schwann cells, fibroblast-like cells, and interspersed mast cells. We propose the term "meissnerian neurofibroma" for this extremely rare variant of neurofibroma.
Keyphrases
  • case report
  • induced apoptosis
  • high resolution
  • machine learning
  • peripheral nerve
  • deep learning
  • wound healing