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Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation.

Andrée-Anne GrossetFrédérick DallaireTien NguyenMirela BirleaJahg WongFrançois DaoustNoémi RoyAndré KougioumoutzakisFeryel AzziKelly AubertinSamuel KadouryMathieu LatourRoula AlbadineSusan PrendevillePaul C BoutrosMichael FraserRobert G BristowTheodorus van der KwastMichèle OrainHervé BrissonNazim BenzerdjebHélène HovingtonAlain BergeronYves FradetBernard TêtuFred SaadFrédéric LeblondDominique Trudel
Published in: PLoS medicine (2020)
In this study, we developed classification models for the analysis of RμS data to differentiate IDC-P, PC, and benign tissue, including HGPIN. RμS could be a next-generation histopathological technique used to reinforce the identification of high-risk PC patients and lead to more precise diagnosis of IDC-P.
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