The fabrication of transferrin-modified two-photon gold nanoclusters with near-infrared fluorescence and their application in bioimaging.
Kangdi HeShengrong YuXiao WangDian LiJia ChenHongmei ZhongQing XuYong-Xiang WuNing GanPublished in: Chemical communications (Cambridge, England) (2021)
Transferrin-modified AuNCs (Tf-AuNCs) with two photon-near infrared (TP-NIR) fluorescence were prepared. For the first time, a novel nanoprobe platform, Tf-AuNCs@MnO2, was developed for the TP-NIR fluorescence imaging and magnetic resonance imaging of living cells and tissues. This platform had high spatiotemporal resolution and a tissue-penetration depth of 300 μm.
Keyphrases
- living cells
- fluorescence imaging
- single molecule
- fluorescent probe
- photodynamic therapy
- magnetic resonance imaging
- high throughput
- energy transfer
- gene expression
- computed tomography
- optical coherence tomography
- sensitive detection
- drug delivery
- magnetic resonance
- silver nanoparticles
- quantum dots
- diffusion weighted imaging