Tuberculosis of the bone marrow with secondary hemophagocytic lympho-histiocytosis presenting as obstructive jaundice: A clinician's challenge for the ages.
Varsha SatheesYasmeen HynniewtaK G LynrahBiswajit DeyAnomitro ChakrabartyDonboklang LynserDebanshu ChakrabortyPublished in: The Indian journal of tuberculosis (2024)
Tuberculosis. a disease of great public concern, is spread through inhalation of micro-droplets from an infected person. Despite lungs being the primary site, there may be multisystemic involvement, very rarely involving bone marrow, a dreaded manifestation of disseminated tuberculosis, associated with high mortality and morbidity. We report a case of tuberculosis of bone marrow with concomitant secondary hemophagocytic lympho-histiocytosis, bringing into light the importance of clinical suspicion and evaluation of bone marrow being a primary site of involvement in patients of disseminated tuberculosis.
Keyphrases
- bone marrow
- mycobacterium tuberculosis
- mesenchymal stem cells
- pulmonary tuberculosis
- hiv aids
- end stage renal disease
- adverse drug
- chronic kidney disease
- ejection fraction
- prognostic factors
- newly diagnosed
- type diabetes
- cardiovascular disease
- peritoneal dialysis
- patient reported outcomes
- risk factors
- cardiovascular events