Dedifferentiation and Proliferation of Artery Endothelial Cells Drive Coronary Collateral Development in Mice.

Gauri ArolkarSneha Krishna KumarHanjay WangKaren M Gonzalez Suraj KumarBhavnesh BishnoiPamela E Rios CoronadoYiping Joseph Woo Kristy Red-Horse Soumyashree Das

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

These data indicate that adult artery endothelial cells fail to drive collateral artery development due to their limited ability to dedifferentiate and proliferate.

Keyphrases

endothelial cells
coronary artery
coronary artery disease
signaling pathway
electronic health record
vascular endothelial growth factor
type diabetes
machine learning
adipose tissue
insulin resistance
high fat diet induced
transcatheter aortic valve replacement