Is CT-based body composition associated with long-term chemotherapy-induced peripheral neuropathy in colorectal cancer survivors?

Debbie SmitFloortje MolsCynthia S BonhofMartijn J L BoursGerard VreugdenhilSandra Beijer

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2022)

Only SAT was associated with total, motor, and sensory CIPN. Based on these results, we cannot conclude that determining the chemotherapy dose based on body composition is preferred over determining the chemotherapy dose based on body surface to prevent CIPN. More research is needed to assess associations of body composition with CIPN, a common side effect of chemotherapy.

Keyphrases

body composition
chemotherapy induced
resistance training
bone mineral density
young adults
locally advanced
radiation therapy
dual energy
rectal cancer