Glucantime reduces mechanical hyperalgesia in cutaneous leishmaniasis and complete Freund's adjuvant models of chronic inflammatory pain.

Suelen Santos da SilvaSandra S MizokamiJacqueline R FantiIdessania N CostaJuliano BordignonIonice FelipeWander R PavanelliWaldiceu Aparecido VerriIvete Conchon Costa

Published in: The Journal of pharmacy and pharmacology (2018)

Our data demonstrated that Glucantime reduced the chronic inflammatory pain induced by L. amazonensis and CFA stimuli by inhibiting the hyperalgesic cytokines production.

Keyphrases

neuropathic pain
chronic pain
pain management
oxidative stress
signaling pathway
machine learning
drug induced