Overall hemostasis potential and aPTT-clot waveform analysis as powerful laboratory diagnostic tools for identification of hemophilia A patients with unexpected bleeding phenotype.

Marija Milos Desiree Coen HerakNida Mahmoud Hourani SoutariJosipa PavicSilva Zupancic-SalekRenata ZadroJovan P Antovic

Published in: International journal of laboratory hematology (2020)

This study emphasizes OHP and aPTT-CWA as a powerful laboratory diagnostic tool in identifying HA patients with unexpected bleeding presentations, with the best results achieved by combining both assays. Global assays should not completely replace FVIII activity measurement but should be a part of the HA diagnostic algorithm.

Keyphrases

risk assessment
human health
high throughput
atrial fibrillation
machine learning