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Decoding of unimanual and bimanual reach-and-grasp actions from EMG and IMU signals in persons with cervical spinal cord injury.

Marvin Frederik WolfRϋediger RuppAndreas Schwarz
Published in: Journal of neural engineering (2024)
Chronic motor impairments of arms and hands as the consequence of a&#xD;cervical spinal cord injury (SCI) have a tremendous impact on activities of daily life.&#xD;A considerable number of people however retain minimal voluntary motor control in the&#xD;paralyzed parts of the upper limbs that are measurable by electromyography (EMG)&#xD;and inertial measurement units (IMUs). An integration into human-machine interfaces&#xD;(HMIs) holds promise for reliable grasp intent detection and intuitive assistive device&#xD;control.&#xD;Approach: We used a multimodal HMI incorporating EMG and IMU data to decode&#xD;reach-and-grasp movements of groups of persons with cervical SCI (n=4) and without&#xD;(control, n=13). A post-hoc evaluation of control group data aimed to identify optimal&#xD;parameters for online, co-adaptive closed-loop HMI sessions with persons with cervical&#xD;SCI. We compared the performance of real-time, Random Forest-based movement&#xD;versus rest (2 classes) and grasp type predictors (3 classes) with respect to their coadaptation&#xD;and evaluated the underlying feature importance maps.&#xD;Main results: Our multimodal approach enabled grasp decoding significantly better&#xD;than EMG or IMU data alone (p<0.05). We found the 0.25 s directly prior to the first&#xD;touch of an object to hold the most discriminative information. Our HMIs correctly&#xD;predicted 79.3 ± STD 7.4 (102.7 ± STD 2.3 control group) out of 105 trials with&#xD;grand average movement vs. rest prediction accuracies above 99.64% (100% sensitivity)&#xD;and grasp prediction accuracies of 75.39 ± STD 13.77% (97.66 ± STD 5.48% control&#xD;group). Co-adaption led to higher prediction accuracies with time, and we could&#xD;identify adaptions in feature importances unique to each participant with cervical&#xD;SCI.&#xD;Significance: Our findings foster the development of multimodal and adaptive HMIs&#xD;to allow persons with cervical SCI the intuitive control of assistive devices to improve&#xD;personal independence.
Keyphrases
  • spinal cord injury
  • machine learning
  • endothelial cells
  • spinal cord
  • healthcare
  • physical activity
  • pain management
  • big data
  • upper limb
  • working memory
  • cerebral palsy