Specific T-Cell Immune Response to SARS-CoV-2 Spike Protein over Time in Naïve and SARS-CoV-2 Previously Infected Subjects Vaccinated with BTN162b2.
Alejandra Natali Vega-MagañaJosé Francisco Munoz-ValleMarcela Peña-RodríguezOliver Viera-SeguraAna Laura Pereira-SuárezJorge Hernández-BelloMariel García-ChagollanPublished in: Vaccines (2022)
We demonstrate that a previous SARS-CoV-2 infection can also impact cellular T-cell response, nAbs production, and serum cytokine concentration. Therefore, the study of T-cell immune response is essential for vaccination scheme recommendations; future vaccine boost should be carefully addressed as continued stimulation by vaccination might impact the T-cell response.