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Effect of the NMDA receptor partial agonist, d-cycloserine, on emotional processing and autobiographical memory.

Runsen ChenLiliana P CapitãoPhilip J CowenCatherine J Harmer
Published in: Psychological medicine (2020)
These findings support the suggestion that low-dose DCS increases specific autobiographical memory retrieval and positive emotional memory. Such effects make it an intriguing agent for further investigation in clinical depression, which is characterised by decreased autobiographical memory specificity and increased negative bias in memory recall. It also underscores the potential role of DCS as an adjunct to cognitive behavioural therapy in depression.
Keyphrases
  • working memory
  • low dose
  • depressive symptoms
  • high dose
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