A simple iodine-DMSO-promoted multicomponent reaction for the synthesis of 2,4-disubstituted dihydrotriazole-3-ones.

Hui LiaoZesheng HuangQiuhua Zhu

Published in: Organic & biomolecular chemistry (2022)

A series of 2,4-disubstituted 1,2,4-triazole-3-ones 4 were prepared via an iodine-DMSO-promoted three-component reaction of formaldehyde, amines and hydrazines in moderate yields.

Keyphrases

dual energy
high intensity
room temperature
electron transfer
magnetic resonance imaging