Influence of Ascorbic Acid as a Growth and Differentiation Factor on Dental Stem Cells Used in Regenerative Endodontic Therapies.

Antje DiederichHanna Juliane FründBogusz TrojanowiczAlexander Navarrete SantosAnh Duc NguyenCuong Hoang-VuChristian Ralf Gernhardt

Published in: Journal of clinical medicine (2023)

AA might be a novel and potent growth promoter of human dental cells. Increasing the properties of human dental pulp cells and the cells of the apical papilla using AA could be a useful factor for further clinical developments of regenerative endodontic procedures.

Keyphrases

stem cells
induced apoptosis
cell cycle arrest
endothelial cells
cell therapy
gene expression
endoplasmic reticulum stress
dna methylation
signaling pathway
oral health
cell death
oxidative stress