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A boosting method to select the random effects in linear mixed models.

Michela BattauzPaolo Vidoni
Published in: Biometrics (2024)
This paper proposes a novel likelihood-based boosting method for the selection of the random effects in linear mixed models. The nonconvexity of the objective function to minimize, which is the negative profile log-likelihood, requires the adoption of new solutions. In this respect, our optimization approach also employs the directions of negative curvature besides the usual Newton directions. A simulation study and a real-data application show the good performance of the proposal.
Keyphrases
  • electronic health record
  • neural network
  • big data
  • machine learning
  • artificial intelligence
  • data analysis