Traditional Cardiovascular Risk Factors Associated with Diagonal Earlobe Crease (Frank Sign) in Mexican Adults: Aging, Obesity, Arterial Hypertension, and Being Male Are the Most Important.
Rogelio Molina-GallardoNomely S Aurelien-CabezasDaniel Tiburcio-JimenezJorge E Plata-FlorenzanoJosé Guzman-EsquivelIram Pablo Rodriguez-SanchezMargarita L Martinez-FierroRoque Molina-OsorioAdrian A De-la-Madrid-CernasJorge Armando Barriguete MeléndezIván Delgado-EncisoPublished in: International journal of hypertension (2024)
In Mexican adults, having an acute coronary syndrome is not the only factor associated with diagonal earlobe crease but also being a man, older than 55 years, having high blood pressure and obesity. Diagonal earlobe crease may simply be caused by changes in the skin and connective tissues of the ears because of the aging process, obesity, and/or being male. These factors, by themselves, enfold cardiovascular risk due to well-known pathophysiological causes.
Keyphrases
- metabolic syndrome
- cardiovascular risk factors
- insulin resistance
- weight loss
- acute coronary syndrome
- blood pressure
- high fat diet induced
- type diabetes
- weight gain
- arterial hypertension
- gene expression
- cardiovascular disease
- physical activity
- hypertensive patients
- body mass index
- atrial fibrillation
- wound healing
- blood glucose