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Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases - the multicenter randomized controlled PUMP trial.

Florian E BuismanM Y V HomsD J GrünhagenW F FilipeR J BenninkM G H BesselinkI H M Borel RinkesR C G BruijnenA CercekM I D'AngelicaO M van DeldenM L DonswijkL van DoornP G DoorneboschJ EmmeringJ I ErdmannN S IJzermanC GrootscholtenJ HagendoornN E KemenyT P KinghamE G KlompenhouwerN F M KokS KoolenK F D KuhlmannM C KuiperM G E LamR H J MathijssenA MoelkerE Oomen-de HoopC J A PuntW W Te RieleJ M L RoodhartR J SwijnenburgW PrevooP J TanisM VermaasM W J VersleijenF P VeugerM J WetermanC VerhoefB Groot Koerkamp
Published in: BMC cancer (2019)
The PUMP trial is registered in the Netherlands Trial Register (NTR), number: 7493 . Date of registration September 23, 2018.
Keyphrases
  • phase iii
  • liver metastases
  • phase ii
  • study protocol
  • clinical trial
  • double blind
  • open label
  • placebo controlled
  • early stage
  • locally advanced
  • low dose
  • squamous cell carcinoma
  • radiation therapy
  • rectal cancer