Immunohistochemical Analysis of Toll-Like Receptors, MyD88, and TRIF in Human Papillary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma.
Yasuhiro Nihon-YanagiMegumi WakayamaNaobumi TochigiFumi SaitoHideaki OgataKazutoshi ShibuyaPublished in: Journal of thyroid research (2021)
These data suggest the involvement of the innate immune system in both PTC and ATC. Specifically, TLR3-mediated TRIF activation was confirmed in PTC and ATC. This provides new insight into thyroid carcinogenesis.