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Transforaminal intrathecal delivery of nusinersen for older children and adults with spinal muscular atrophy and complex spinal anatomy: an analysis of 200 consecutive injections.

John J WeaverDanial K HallamJeffrey Forris Beecham ChickSandeep VaidyaDavid S ShinNiranjana NatarajanNassim RadJoseph ReisKevin S H KooGiridhar M ShivaramAshley ThibodeauSusan ApkonEric James Monroe
Published in: Journal of neurointerventional surgery (2020)
Transforaminal intrathecal delivery of nusinersen is feasible and safe for gaining access in patients with distorted spinal anatomy. The use of CBCT delineates anatomy and optimizes needle trajectory during the initial encounter, and may be used selectively for subsequent procedures.
Keyphrases
  • minimally invasive
  • spinal cord
  • ultrasound guided
  • young adults
  • physical activity
  • magnetic resonance imaging
  • magnetic resonance
  • image quality
  • computed tomography
  • platelet rich plasma
  • contrast enhanced