Ex vivo disease modelling of Rett syndrome: the transcriptomic and metabolomic implications of direct neuronal conversion.

Beren Karaosmanoğlu Gozde Imren M Samil OzisinTuba ReçberPelin Ozlem Simsek KiperGoknur HalilogluMehmet AlikaşifoğluEmirhan NemutluEkim Zihni TaşkiranGulen Eda Utine

Published in: Molecular biology reports (2024)

The present findings provide valuable insights into the molecular and metabolic landscape of Rett syndrome, emphasizing the importance of combining omic data to enlighten the molecular pathophysiology of this syndrome.

Keyphrases

case report
single cell
single molecule
electronic health record
rna seq
deep learning
artificial intelligence