Is LDL cholesterol associated with long-term mortality among primary prevention adults? A retrospective cohort study from a large healthcare system.
Kevin E KipDavid M DiamondSuresh MulukutlaOscar C MarroquinPublished in: BMJ open (2024)
Among primary prevention-type patients aged 50-89 years without diabetes and not on statin therapy, the lowest risk for long-term mortality appears to exist in the wide LDL-C range of 100-189 mg/dL, which is much higher than current recommendations. For counselling these patients, minimal consideration should be given to LDL-C concentration.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- cardiovascular disease
- low density lipoprotein
- type diabetes
- prognostic factors
- cardiovascular events
- mesenchymal stem cells
- patient reported outcomes
- adipose tissue
- metabolic syndrome
- hepatitis c virus
- bone marrow
- hiv infected
- replacement therapy