Characterizing red blood cell age exposure in massive transfusion therapy: the scalar age of blood index (SBI).

Stacia M DeSantisDerek W Brown Allison R JonesJose-Miguel YamalJean-Francois PittetRakesh P PatelCharles E WadeJohn B HolcombHenry Wangnull null

Published in: Transfusion (2019)

SBI is a simple scalar metric of blood age that accounts for the relative distribution of RBCs among age categories. Transfusion of older RBCs is associated with 24-hour and 30-day mortality, after adjustment for total units and clinical covariates.

Keyphrases

red blood cell
cardiac surgery
blood pressure
physical activity
stem cells
sickle cell disease
middle aged
cell therapy