High serum angiopoietin-2 level predicts non-regression of liver stiffness measurement-based liver fibrosis stage after direct-acting antiviral therapy for hepatitis C.
Naoki KawagishiGoki SudaMegumi KimuraOsamu MaeharaTomoe ShimazakiRen YamadaTakashi KitagatayaTaku ShigesawaKazuharu SuzukiAkihisa NakamuraMasatsugu OharaMachiko UmemuraMasato NakaiTakuya ShoMitsuteru NatsuizakaKenichi MorikawaKoji OgawaYusuke KudoMutsumi NishidaNaoya SakamotoPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2020)
Evaluation of serum Ang2 levels before DAA therapy is important. Our results provide a novel mechanistic insight into non-regression of liver stiffness after DAA therapy. Long-term and larger studies are required.