KMT2C Mutations in Diffuse-Type Gastric Adenocarcinoma Promote Epithelial-to-Mesenchymal Transition.

Soo-Jeong ChoChanghwan YoonJun Ho LeeKevin K ChangJian-Xian LinYoung-Ho KimMyeong-Cherl KookBülent Arman AksoyDo Joong ParkHassan AshktorabDuane T SmootNikolaus SchultzSam S Yoon

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

KMT2C is frequently mutated in certain populations with DGA. KMT2C loss in DGA promotes EMT and is associated with worse overall survival.

Keyphrases

epithelial mesenchymal transition
squamous cell carcinoma
low grade
locally advanced
free survival
high grade
rectal cancer