Prognostic Relationship Between Coronary Artery Calcium Score, Perfusion Defects, and Myocardial Blood Flow Reserve in Patients With Suspected Coronary Artery Disease.
Krishna K PatelPoghni A Peri-OkonnyRaed QarajehFemina S PatelBrett W SperryA Iain McGhieRandall C ThompsonKevin F KennedyPaul S ChanJohn A SpertusTimothy M BatemanPublished in: Circulation. Cardiovascular imaging (2022)
Use of anatomic testing such as CACS of 0 to avoid myocardial perfusion imaging in symptomatic patients could lead to missing microvascular dysfunction in 4 out of 10 patients, a finding associated with a high mortality risk. Higher CACS was independently associated with the risk of death but did not provide incremental prognostic value over positron emission tomography with MBFR.
Keyphrases
- positron emission tomography
- end stage renal disease
- coronary artery
- coronary artery disease
- blood flow
- newly diagnosed
- ejection fraction
- chronic kidney disease
- computed tomography
- prognostic factors
- magnetic resonance imaging
- pulmonary artery
- heart failure
- cardiovascular disease
- oxidative stress
- patient reported outcomes
- left ventricular
- photodynamic therapy
- mass spectrometry
- acute coronary syndrome
- contrast enhanced