Treatment of mycophenolate-resistant immune-related organizing pneumonia with infliximab.
Guacimara Ortega SanchezKathleen JahnSpasenija SavicAlfred ZippeliusHeinz LaubliPublished in: Journal for immunotherapy of cancer (2018)
This case describes a not well-studied situation, in which a mycophenolate-resistant PD-1 blocker-associated pneumonitis was successfully treated with a TNFα neutralizing antibody. The outcome of this case suggests that infliximab might be the preferable option compared to classical immunosuppressants in the case of steroid-resistant/-dependent late onset pulmonary irAEs.