Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2.

Fuhai LiAndrew P MichelsonRandi ForakerMing ZhanPhilip R O Payne

Published in: BMC medical informatics and decision making (2021)

The integrative genomics data analysis and results can be helpful to understand the associated molecular signaling pathways within host cells, and facilitate the discovery of effective drugs for COVID-19 treatment.

Keyphrases

sars cov
induced apoptosis
data analysis
coronavirus disease
cell cycle arrest
signaling pathway
respiratory syndrome coronavirus
endoplasmic reticulum stress
gene expression
high throughput
cell proliferation
replacement therapy