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KDM4C represses liver fibrosis by regulating H3K9me3 methylation of ALKBH5 and m6A methylation of snail1 mRNA.

Hua Ying ZhouBing Qing WangMeng Xuan ChenYi Fan WangYong Fang JiangJing Ma
Published in: Journal of digestive diseases (2024)
KDM4C decreases H3K9me3 methylation to upregulate ALKBH5 and subsequently inhibits snail1, ultimately impeding liver fibrosis.
Keyphrases
  • liver fibrosis
  • genome wide
  • epithelial mesenchymal transition
  • dna methylation
  • gene expression
  • signaling pathway