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Development and evaluation of a novel combined perfusion decellularization heart-lung model for tissue engineering of bioartificial heart-lung scaffolds.

Alina ZubarevichAnja OsswaldLukman AmanovArian Arjomandi RadBastian SchmackArjang RuhparwarAlexander Weymann
Published in: Artificial organs (2022)
We present a novel model of combined perfusion and decellularization of heart-lung organ-blocs. This model is the first step on the pathway to creating bioengineered transplantable heart-lung scaffolds. We believe that further development of this technology could provide a life-saving conduit, significantly reducing the risks of heart-lung failure surgery and improving postoperative quality of life.
Keyphrases
  • tissue engineering
  • heart failure
  • atrial fibrillation
  • minimally invasive
  • patients undergoing
  • coronary artery disease
  • magnetic resonance
  • contrast enhanced
  • climate change
  • acute coronary syndrome