Development and evaluation of a novel combined perfusion decellularization heart-lung model for tissue engineering of bioartificial heart-lung scaffolds.
Alina ZubarevichAnja OsswaldLukman AmanovArian Arjomandi RadBastian SchmackArjang RuhparwarAlexander WeymannPublished in: Artificial organs (2022)
We present a novel model of combined perfusion and decellularization of heart-lung organ-blocs. This model is the first step on the pathway to creating bioengineered transplantable heart-lung scaffolds. We believe that further development of this technology could provide a life-saving conduit, significantly reducing the risks of heart-lung failure surgery and improving postoperative quality of life.